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Oxytocin Administration and the Prevention of Postpartum Hemorrhage
Brooks, Heather
Brooks, Heather
Abstract
Description
Postpartum hemorrhage (PPH) is a large issue in the world of labor and
delivery, the rates of PPH are getting worse as time goes on. Oxytocin is a
widely used and very effective medication used to prevent PPH during the third
stage of labor. This is an extensive literature review of evidence based
research on the subject of PPH and oxytocin administration. This study aims to
determine if oxytocin is an effective prophylactic medication, compare oxytocin
to other uterotonic options and evaluate the most effective route of
administration. For the purpose of this study, PPH is defined as >500mL of
blood loss, and severe PPH is >1000mL of blood loss within the first 24
hours after delivery. To conduct the literature review, a variety of online research platforms
were used. Key words and phrases that were used included "oxytocin and
postpartum hemorrhage", "postpartum hemorrhage prevention", and
"intravenous versus intramuscular oxytocin". The resulting studies
were then evaluated and compared to find the most reliable research. The
results showed that oxytocin is effective in preventing PPH >500mL and may
be effective in preventing severe PPH of >1000mL. Along with that,
intravenous was found to be the most effective route of administration.
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University of Wyoming. Libraries
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Keywords
postpartum hemorrhage,oxytocin,Uterotonics,Carbetocin,postpartum hemorrhage risk factors,prevention of postpartum hemorrhage,Active management of third stage of labor